Kidney-Health

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We are less aware that lifetime health problems you may have or occur in future due to your genes and your strengths which you are gifted by your parents.Avastu Genetics help you to recognise them and also help you to cure your genetic health problems through counselling, diet and nutrition’s. It is a onetime Investment Program includes 105 Phenotypes tests which will guide to identify your Generic Strength and protect you from your Genetics Problem throughout your life.


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Risk of Hyperuricemia

Uric acid is the final enzymatic product of purine metabolism and it has the ability to scavenge oxygen radicals and protect the erythrocyte membrane from lipid oxidation. However, elevated serum uric acid (hyperuricemia) is associated with significantly increased risk for gout, cardiovascular disease, chronic kidney disease (CKD), and type 2 diabetes mellitus. Hyperuricemia has received increasing attention as a major public health problem in China because of its high prevalence and the associated increases in the risk of gout, hypertension, cardiovascular disease and CKD. What is more, hyperuricemia also plays an important role in metabolic related diseases, such as metabolic syndrome, diabetes and non-alcoholic fatty liver disease
Uric acid is formed when purines break down in your body. Purines are chemicals found in certain foods such as:
1. Red meat
2. Organ meat
3. Sea food
4. Beans
Risk factors:
1. Alcohol use
2. Some medications, particularly medications for heart disease
3. Lead exposure
4. Pesticide exposure
5. Kidney disease
6. High blood pressure
7. High blood glucose levels
8. Hypothyroidism
9. Obesity
10. Extreme levels of physical activity
Hyperuricemia symptoms:
1. Gout: Gout, sometimes called gouty arthritis, occurs in about 20 percent of people with hyperuricemia.
2. Tophaceous gout: If you’ve had hyperuricemia for several years, uric acid crystals can form clumps called tophi. These hard lumps are found under your skin, around your joints, and in the curve at the top of your ear.
3. Kidney stones: Uric acid crystals can cause a build-up of stones in your kidneys. Often, the stones are small and are passed in your urine. Sometimes, they can become too large to pass and block parts of your urinary tract

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Autosomal Dominant Polycystic Kidney Disease Risk

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the growth of numerous cysts in the kidneys. Symptoms vary in severity and age of onset, but usually develop between the ages of 30 and 40. ADPKD is a progressive disease and symptoms tend to get worse over time. The most common symptoms are kidney cysts, pain in the back & the sides and headaches. Other symptoms include liver and pancreatic cysts, urinary tract infections, abnormal heart valves, high blood pressure, kidney stones, and brain aneurysms. ADPKD is most often caused by changes in the PKD1 and PKD2 genes, and less often by changes in the GANAB and DNAJB11 genes. It is inherited in a dominant pattern. Symptoms:
The symptoms and severity of Autosomal Dominant Polycystic Kidney Disease (ADPKD) vary from person to person. The most common symptoms are formation of kidney cysts, pain in the back and the sides and headaches. These symptoms may get worse over time. Eventually the formation of multiple kidney cysts leads to kidney damage and kidney failure.
People with ADPKD may also experience the following complications:
1. High blood pressure
2. Urinary tract infections—specifically in the kidney cysts
3. Blood in the urine (hematuria)
4. Liver and pancreatic cysts
5. Abnormal heart valves
6. Kidney stones
7. Brain aneurysm